·Automobiles accelerate the opening of new energy vehicle technology patents

Recently, Ford Motor Co. claimed to disclose thousands of electric vehicle patents and pending patents in its hands to the outside world. Prior to this, Tesla announced the opening of all patents held by the company. Toyota Motor also announced the availability of 5,680 patents for fuel cell technology worldwide.
Relevant information shows that Tesla has 203 electric vehicle technology patents, plus 280 items still in the process of approval, a total of 483 electric vehicle technology patents. Of the 5,680 patents shared by Toyota, about 1,970 are related to fuel cell stack technology, 290 are related to high-pressure hydrogen tank technology, 3,350 are related to fuel system software technology patents, and 70 are related to hydrogen generation and supply technologies. Ford's patents are concentrated in the field of electrified vehicle technology. Currently, there are 650 approved and another 1,000 patents pending approval.
Why did multinational auto companies that have always regarded technology patents as their life choose to open new energy auto technology patents?
According to industry experts, from the perspective of the world, new energy vehicles have not yet formed a large industrial scale. The development of new energy markets cannot be completed by only one enterprise or one country. It is necessary for the entire industry to work together to overcome difficulties. It is even more necessary for countries around the world to join the major car companies to make the cake bigger. Technology disclosure will benefit the new energy to form an industrial scale.
“The most fundamental reason why multinational car companies open up new energy vehicle technology is that they have seen the future development of new energy. This field is hot on the global scale and has great potential.” In contrast, the traditional energy vehicle market The development has matured, and the major automakers such as powertrain and modular platform have been developed in the early stage, and all have their own technical routes. The impact of liberalizing patents is not as good as the new energy field. Compared with the molding technology of traditional automobiles, the new energy industry still has a large space for exploration. In addition, the Chinese government attaches great importance to the new energy automobile industry, and multinational auto companies want to use the benefits of policies to vigorously develop new energy vehicles in China.
Under the market economy environment, operators are not profitable, and strive to make bigger market cakes. It is the original intention of multinational auto companies to open technology patents. The biggest profit point and difficulty of new energy vehicles is the battery, and the standards of various battery manufacturers are different. The large-scale open technology of car companies has also contributed to the environmental protection and new energy markets, and successfully produced an emotional card. Moreover, the release of technology patents can play a role in the government's development of new energy-related standards.
In addition, due to the nature of the company and the stage of development, under the fundamental purpose of expanding the market, each of the multinational auto companies that have announced their technology patents has its own small ninety-nine. Tesla, which started with the Internet, is not stable in the automotive industry. Its open technology patents are to attract more participants to jointly resist market risks and pave the way for subsequent service profit points. Toyota and Ford are more beautifying themselves, shocking their competitors through technology sharing and improving their brand image.
The disclosure of new energy vehicle technology patents will reduce the barriers to entry, and the new energy vehicle industry will surely emerge a group of potential new entrants and bring a better development platform. However, in the new energy vehicle terminal consumer market, the impact of the current technology disclosure is still only in the industry itself, the technology is not invested in the physical car, in the short term will not have much impact on the overall consumption chain, the market of new energy vehicles There is still a long way to go before the promotion.

Upadacitinib Intermediates

Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage and bone destruction, leading to co-morbidities. Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies. The etiology of the disease is mostly unknown; however, the role of JAK as a driver of immune-mediated conditions was discovered, leading to the use of JAK as therapeutic targets for rheumatoid arthritis. To reduce dose-related toxicity (as seen with some pan-JAK inhibitors) without significantly affecting efficacy, more selective JAK1 inhibitors, upadacitinib and [filgotinib], were developed. The FDA approved Upadacitinib in August 2019 for the treatment of adults with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. In December 2019, it was additionally approved by the European Commission for the same indication in patients with inadequate response or intolerance to one or more DMARDs and can be used as monotherapy or in combination with methotrexate. Upadacitinib is marketed under the brand name RINVOQâ„¢ for oral administration. It is currently being investigated in several clinical trials assessing its therapeutic effectiveness in other inflammatory diseases, such as psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, and atopic dermatitis.

Upadacitinib Cas 1201187-44-1,Upadacitinib Cas 1428243-26-8,Upadacitinib Intermediate Cas 1201187-44-1,Upadacitinib Intermediate Cas 1428243-26-8

 Shandong Haohong Biotechnology Co., Ltd. , https://www.haohongpharma.com